Prof Alvaro MATA


Queen Mary, University of London, UK


Alvaro Mata’s research aims to bridge supramolecular chemistry, out-of-eqiulibrium processes, engineering, and biology to develop supramolecuar bioengineering strategies to develop new biofabrication strategies and materials that exhibit strutural complexity, hierarchical order, and dynamic propertie such as the capacity to grow and self-heal. He holds a Bachelor’s Degree from the University of Kansas, a Master’s Degree from the University of Strathclyde, and a Doctor of Engineering Degree from Cleveland State University. During his doctorate he worked at The Cleveland Clinic with Prof. Shuvo Roy and from 2005-2008 as a Postdoctoral Fellow with Prof. Samuel Stupp at Northwestern University. From 2008-2013 he was Head of the Nanotechnology Platform at Parc Científic Barcelona in Spain and is currently Professor in Biomaterials and Bioengineering and Director of the Institute of Bioengineering at Queen Mary University of London.

https://www.matabioengineering.com/

https://scholar.google.co.uk/citations?user=RvPS0AwAAAAJ&hl=en

 

Transforming proteins into functional biomaterials for complex tissue engineering

Abstract

There is great interest to develop new materials that resemble those of biological systems such as hierarchical organization and the capacity to grow or self-heal. To this end, supramolecular chemistry offers an exciting opportunity to grow materials with nanoscale precision. However, the ability to transform molecular design into functional devices with utility at the macroscale remains a challenge. The talk will describe new strategies that integrate supramolecular chemistry with engineering principles to develop practical materials with tuneable and advanced properties such as hierarchical organisation (1,2), the capacity to grow (2,3), tuneable mechanical properties2, and anisotropic bioactivity (4). These materials are being used for the regeneration of tissues such as enamel, bone, and blood vessels as well as more biologically relevant in vitro models for applications in cancer and neurological disorders.  

References

(1) Hedegaard et al (2018). Advanced Functional Materials 10.1002/adfm.201703716. 

(2) Elsharkawy et al (2018). Nature Communications 10.1038/s41467-018-04319-0. 

(3) Inostroza-Brito et al (2015). Nature Chemistry 7(11), 897-904. 10.1038/nchem.2349.

(4) Aguilar et al (2017). Advanced Functional Materials 10.1002/adfm.201703014.

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